Restless Legs Syndrome

WARNING: This Miracle Medication will stop RLS immediately


Frustrated man awake in bed with RLS rubbing legs in bed
                             PLEASE Stop Twitching!

Yep. It stopped my RLS on Day One and has worked flawlessly ever since.

WHAT is this Miracle Medication?

Great question, and I promise to answer it shortly. But first, what exactly is RLS?

RLS stands for Restless Legs Syndrome, and is a neurological condition that creates uncomfortable sensations in the legs that are only relieved by moving the legs.

It’s also known as Willis-Ekbom disease, named for the two doctors who discovered the disorder. An estimated 5% of the general population and 10% of those over age 65 have RLS.

Dr. Christopher Earley, RLS Specialist
Dr. Christopher Earley, RLS Specialist

It usually starts after going to bed, and is a maddening cycle that totally robs your sleep. Sometimes described as “twitching”, “tingling”, “aching” or “crawling”, RLS is a condition that can greatly impact one’s health, career and family.

RLS can be in one or both legs, and its location varies. For me, all of my RLS twitches are in my thighs, while my sister’s RLS only happens in her calves. A small minority of patients also experience RLS symptoms in their arms.

RLS usually gets worse after surgery, as neural connections are often severed. I had both knees replaced this past year, and had a significant spike in my RLS symptoms. This has been the only time I’ve increased dosage, but later I reverted back to my original dosage.

Even though Restless Legs Syndrome sounds decidedly non-clinical, the name Willis–Ekbom Disease is so awkward that the new name simply isn’t sticking.

In fact, the physician who manages my RLS – Dr. Christopher Earley, co-founder of the Center for Restless Legs Syndrome at Johns Hopkins – is one of the leading RLS physicians in the world, and he still calls it RLS. So do I.

Typical RLS Treatment

If you currently suffer from RLS, you probably started by trying over-the-counter and/or lifestyle remedies. They may help, but if the RLS continues, you will seek relief from your doctor, who will probably give you a prescription for one of these medications that stimulate Dopamine production:

  • Mirapex (pramipexole)


  • Requip (ropinirole)


  • Sinemet (levodopa/carbidopa)

But here’s the problem: up to 75% of people who take these dopamine medications for RLS will experience augmentation, which means that not only does the medicine stop working, it actually makes your RLS worse.

Yikes! Who wants their RLS to get WORSE?

In fact, I have a personal story about this very situation. My sister with RLS had a doctor who unknowingly prescribed her 3x the maximum recommended dosage of Mirapex. After meeting with Dr. Earley, she nearly had to be hospitalized to manage her withdrawal from Mirapex.

Once clean, she was given the RLS Miracle Medication – which worked for her on Day One as well!

And NOW ... the Miracle Medication for RLS

Okay … now it’s time to tell you about the RLS Miracle Medication.

But it’s going to shock you.

If you want to stop RLS immediately, the miracle Rx is low-dosage Methadone (2.5 to 20 mg).


That’s right, Methadone—the narcotic, the opioid, the same drug used by addiction clinics to wean hard-core addicts off heroin.

When Dr. Earley first told me that Methadone was by far the best Rx solution for RLS, I was very skeptical. I was not too keen on taking an addictive opioid used by heroin addicts. But by that time, my Mirapex has augmented so badly that I was getting almost no sleep, and I would’ve taken almost anything to get some relief.

That was 14 years ago, and I can honestly tell you that Methadone may have saved my life.

If I had not gotten relief from my RLS, and continued getting so little sleep, I’m convinced I would’ve had a medical breakdown. The reason that prisoners of war are often deprived of sleep is that it breaks down their defenses. They are then more likely to share important enemy intelligence, and it eventually starts to make them crazy … literally.

Benefits of Low-Dosage Methadone for RLS

Three (3) important benefits of low-dosage Methadone for RLS patients are:

  1. It Works for Nearly All RLS Patients – Research has proven that 90% of patients with RLS will respond very well to low-dosage Methadone.


  2. Almost No Chance of Dependence – Dr. Earley has treated RLS patients at Johns Hopkins for over 25 years with low-dosage Methadone, and ZERO PATIENTS have had dependence issues. NOT ONE. Why? Dr. Earley told me when RLS patients take Methadone, it connects to different brain receptors than regular people, so therefore no patients get hooked. For me, that’s been true—when I take Methadone, I never get that loopy feeling that usually comes with pain medicine.


  3. Effective Long-Term without Increased Dosage – Dr. Earley’s research has shown that after 10 years, 85% of RLS patients who started on Methadone were still taking the Rx successfully, as compared to 20% with dopamine drugs like Mirapex. Both my sister and I have been taking Methadone 13+ years, and it works as well today as it did on Day One – without increasing the dosage.

So here’s the BOTTOM LINE: if you have RLS, ask your doctor to read the following clinical information from Johns Hopkins about RLS:

Or better yet, print off and take some of these studies and links to your doctor and ask him/her to review them. Then hopefully s/he will consider prescribing low-dosage Methadone for your RLS. With all of the opioid abuse out there, some clinicians won’t prescribe Methadone, which I understand, but I think they should put their patients’ legitimate needs over their fears.

But sometimes it doesn’t work. I live in rural southwest Virginia in a small town called Abingdon, and our region has a serious problem with opioid abuse and addiction. My primary care doctor listened to my request, then refused to consider prescribing Methadone.

So I drive seven hours every year to Baltimore to meet with Dr. Earley at Johns Hopkins in order to continue getting my Methadone Rx. He has patients from all over the country who do the same. It’s totally worth it.

And even though Dr. Earley is going to retire in a few years—despite my protests  —there will always be physicians at Johns Hopkins’ Center for Restless Legs Syndrome who can prescribe Methadone for RLS patients. Below is the Johns Hopkins contact information:

For RLS appointments or evaluations:

· Maryland patients                        Call 410-550-0571 or Request Appointment Online

· U.S. patients outside MD            Call 855-695-4872 or Request Appointment Online

· International Patients                  Call 1-410-502-7683 or Request Appointment Online


Center for Restless Legs Syndrome
Johns Hopkins Sleep Disorders Center
Allergy & Asthma Center, 4th Floor
5501 Hopkins Bayview Circle
Baltimore, MD 21224

So don’t suffer any longer — and good luck in getting relief from your RLS!